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Well-differentiated liposarcoma

3 associated genes
4 signs/symptoms

PROTEIN INTERACTIONS: 1

X-linked lymphoproliferative disease

2 OMIM references -
2 associated genes
8 signs/symptoms

Well-differentiated liposarcoma

X-linked lymphoproliferative disease

CDK4	(UniProt - OMIM)		SH2D1A	(UniProt - OMIM)
HMGA2	(UniProt - OMIM)		XIAP	(UniProt - OMIM)
MDM2	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MDM2	(0.78)	XIAP

Citations in the biomedical literature:

Well-differentiated liposarcoma		X-linked lymphoproliferative disease
	Synonym(s): - ALT - Atypical lipoma - Atypical lipomatous tumor - WDLS		Synonym(s): - Duncan disease - Purtilo syndrome - XLP

	Classification (Orphanet): - Rare oncologic disease		Classification (Orphanet): - Rare genetic disease - Rare immune disease - Rare oncologic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: - Type of inheritance: x-linked recessive

	External references: No OMIM references No MeSH references		External references: 2 OMIM references - 1 MeSH reference: D008232

Well-differentiated liposarcoma		X-linked lymphoproliferative disease
	Very frequent - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling Occasional - Functional anomalies of the kidney and the urinary tract - Intestinal transit disorder		Very frequent - T-cell deficiency / cellular immunity deficiency - X-linked recessive inheritance Frequent - Agammaglobulinemia / hypogammaglobulinemia / B-cell deficiency - Hepatomegaly / liver enlargement (excluding storage disease) - Lymphadenopathy / polyadenopathies - Lymphoma - Splenomegaly Occasional - Anaemia